The average journey time from Frankfurt (Main) to Prague by train is 8 hours 3 minutes, although on the fastest services it can take just 6 hours 51 minutes. Around 32 trains per day travel the 256 miles (413 km) between these two destinations. Direct trains are usually available every day on the route to Prague. If you enjoy road trips and prefer driving, it’s possible to travel from Manchester to Prague by car. The distance by road is approximately 1,300 kilometers or 810 miles. The route takes you through several countries, including England, France, Belgium, Germany, and finally reaching the Czech Republic where Prague is located. Get a quick answer: It's 3,893 miles or 6266 km from Manchester (New Hampshire) to Prague, which takes about 8 hours, 17 minutes to fly. The total straight line distance between Prague and Manchester is 1205 KM (kilometers) and 190.44 meters. The miles based distance from Prague to Manchester is 748.9 miles. This is a straight line distance and so most of the time the actual travel distance between Prague and Manchester may be higher or vary due to curvature of the road . Distance from Manchester to Prague (Manchester–Boston Regional Airport – Václav Havel Airport Prague) is 3887 miles / 6255 kilometers / 3378 nautical miles. See also a map, estimated flight duration, carbon dioxide emissions and the time difference between Manchester and Prague. Flight information. Live Ryanair arrivals and departures from Manchester Airport Terminal 3. Check the status of your flight and see your itinerary. Cheap flights from Manchester (MAN) to Prague (PRG) Prices were available within the past 7 days and start at CA $61 for one-way flights and CA $169 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. Get a quick answer: It's 1,012 miles or 1629 km from Prague to Manchester, which takes about 17 hours, 46 minutes to drive. mgQ8Xg9.